In the 5 years since publication of the first edition of the Handbook of Drug–

Nutrient Interactions, new perspectives have emerged and new data have been

generated on the subject matter. We have attempted to capture this in the current

chapters which have all been revised or are completely new to this edition.

This book is intended for use by physicians, pharmacists, nurses, dietitians, and

others whether in training, in clinical practice, in academia, or in research. The book

has retained the goals of the previous edition which include improving recognition

and management of drug–nutrient interactions. The topic of drug–nutrient interactions

is significant for clinicians and researchers alike. For clinicians in particular,

the book offers a guide for understanding, identifying or predicting, and ultimately

preventing or managing drug–nutrient interactions to optimize patient care. The

book provides a scientific look behind many drug–nutrient interactions, examines

their relevance, offers recommendations, and suggests research questions to be

explored. Although not inclusive of every potential interaction, we hope that the

breadth and depth of the book will challenge readers to actively engage in improving

the quantity and quality of data in the field. This will help increase the profile of

drug–nutrient interactions to that comparable with drug–drug interactions in the

care of patients.